ABZ Science
The Structure, Function and Genetics of Z-DNA and Z-RNA
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In contrast to the common right-handed A- and B-conformations of RNA and DNA, their Z-conformations are left-handed. Starting with the crystallization of Z-DNA in 1979, biophysical and biochemical studies have yielded many unanticipated and fascinating insights into this class of higher energy nucleic acid conformations.
Recent discoveries of biological functions for Z-conformations have demonstrated important roles in immunity against infectious agents and cancers. More generally, research on Z-conformations underscore the impact of alternative RNA and DNA conformations in both normal cellular function and disease. They further emphasize that regulatory information is encoded by structure in addition to sequence.
The 'ABZ Meeting 2024' was held on November 20!
The meeting was virtual (Zoom)
November 20th, 2024
10 am – 4:30 pm EDT (US Eastern Time)
7 am – 1:30 pm PST
3 pm – 9:30 pm GMT (UK Time)
11 pm (Nov 20th) – 5:30 am (Nov 21th) SGT
0 am (Nov 21th) – 6:30 am (Nov 21th) JST
Participation is free of charge
As we have done successfully in past meetings, we featured speakers from many different fields to increase awareness of the many innovative approaches available to further advance the field. Our aim is to build community and to foster multidisciplinary collaborations.
Program:
Register here
Questions to info@abz.bio
Looking for a proper journal to publish your latest Z-NA research?
Molecules still accepts submissions to a Z-DNA and Z-RNA special issue
Past meetings:
ABZ Meeting 2022, second leg, September 7 (Asia)/September 6 (US)
ABZ Meeting 2022, first leg, May 25
For more information klick on the meetings
Browse the joint special issue "Z-DNA and Z-RNA: from Physical Structure to Biological Function" in Molecules and International Journal of Molecular Sciences
Contacts:
E-mail: info@abz.bio
Dr. Quentin Vicens
Department of Biology and Biochemistry, University of Houston
E-mail: qvicens@uh.edu
Dr. Beat Vögeli
Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora
E-mail: beat.vogeli@cuanschutz.edu
Dr. Alan Herbert
Discovery, InsideOutBio, Inc., Charlestown, MA, USA
E-mail: alan.herbert@insideoutbio.com
Dr. Karen Vasquez
University of Texas at Austin
E-mail: karen.vasquez@austin.utexas.edu
Dr. Yukio Kawahara
Osaka University
Email: ykawahara@rna.med.osaka-u.ac.jp
Dr. Andrew Oberst
University of Washington
Email: oberst@uw.edu
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